SynchroGait (DMRT3-Variants) P516

Background

The movement of a horse relies on a complex interneuronal structure in the spinal cord. Mutations in DNA involved in forming the spinal cord might interfere in the way the left?right alternation of limbs are regulated. This causes altered gaites in horses.

Test specific information

This test is performed by Certagen.

Age

The genetic factor is continuously present, and will always be visible.

Throughput

Normally the result can be expected within 25 working days. This turn-around-time starts when both the sample and the fully filled-out and signed submission form have been received.

Location of disease or trait

-

Breed dependence

This DNA test is available for the following breeds: Icelandic Horse.

Sample type

For this DNA test we accept the following materials: Hair, Blood EDTA, Blood Heparin, Tissue. Please contact PharmaDNA if you wish to submit other material as listed.

Result

An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.

Inheritance

This genetic factor is inherited in an autosomal, recessive mode. This means, that the individual can be homozygote normal (free of this disposition), heterozygote carrier (heterozygous, the individual can inherit the disposition) or homozygote disposed (homozygous, the individual bears the disposition and will inherit it).

Severity of Disease

-